25 results

Preclinical Research Shows Senescent Cell Removal Improves Cognitive Function

https://discoverysedge.mayo.edu/2021/01/27/preclinical-research-shows-senescent-cell-removal-improves-cognitive-function-during-aging/
Preclinical Research Shows Senescent Cell Removal Improves Cognitive Function ... findings indicate that the removal of senescent cells in aging mice improves cognitive ... mice appear in Aging Cell. Senescent cells are those cells in the body that have ... ignored the order to expire. These cells exist in a suspended state. They are ... linger, spewing out toxic chemicals. The cells and their toxic chemicals often are

A Zombie Cell Expedition and Other Senescent Cell Research

https://discoverysedge.mayo.edu/2021/11/10/a-zombie-cell-expedition-and-other-senescent-cell-research/
A Zombie Cell Expedition and Other Senescent Cell Research ... damaged cells that linger and cause chaos in the body. Called senescent cells, these ... signals and disrupt the function of the cells in their neighborhood. They have been ... neurodegenerative and cardiovascular diseases as well as cancer. While potential therapies ... Mayo Clinic scientists to remove senescent cells have reached the first stage in

Mayo Clinic Research News – Zombie Cell Edition

https://discoverysedge.mayo.edu/2020/05/12/mayo-clinic-research-news-zombie-cell-edition/
Research News – Zombie Cell Edition ... There are times when a cell must cease its work ... of a normal cell’s limited number of divisions, or when a cell is heading down ... a pathway that leads to cancer. Cells that are stopped from dividing but ... are called senescent cells. These cells, sometimes called zombie cells, are

Removing Senescent Cells Stops Extra-Skeletal Bone Growth in Mice

https://discoverysedge.mayo.edu/2022/02/10/removing-senescent-cells-stops-extra-skeletal-bone-growth-in-mice/
Removing Senescent Cells Stops Extra-Skeletal Bone Growth in Mice ... senescent cells from the body may prove a treatment for yet another condition ... this case it’s a genetic condition called fibrodysplasia ossificans progressiva ... their 50s. Senescent cells, sometimes called zombie cells, stop functioning ... body, circulating and causing other cells to malfunction and produce symptoms

Toxic Cellular Ooze Linked to Biological Age, Disease and Disability

https://discoverysedge.mayo.edu/2020/10/20/zombie-cells-toxic-ooze-linked-to-disease-disability-biological-age/
Cells in the body usually do what they’re ... cues, cells divide, grow, shrink or die as needed. But there are some cells that ... order to expire: senescent cells. Sometimes called "zombie cells" for their undead ... undead lingering, senescent cells have triggered the body’s kill command, but ... Illustration of normal cells (pink) and senescent cells (green). Credit: Donna

Balancing Damage and Protection, Neutrophils May Lead to Cell Aging

https://discoverysedge.mayo.edu/2021/03/25/balancing-damage-and-protection-neutrophils-may-lead-to-cell-aging/
Neutrophils May Lead to Cell Aging ... The action of an immune cell called a neutrophil may ... in nearby cells which, over time, may lead to cellular senescence. This new ... new concept may help clarify cell aging. It also suggests targeting neutrophils ... Neutrophils, Senescent Cells The immune system is a collection of cells and proteins

Exercise Reduces Indicators of Senescent Cells in the Body

https://discoverysedge.mayo.edu/2021/06/09/exercise-reduces-indicators-of-senescent-cells-in-the-body/
Indicators of Senescent Cells in the Body ... Senescent cells, sometimes called zombie ... zombie cells, are major contributors of aging and can contribute to symptoms ranging ... decline and frailty. They are regular cells that no longer function properly, but ... exercise can reduce the signs of senescent cells and lessen some of the symptoms

Rocketing Ahead

https://discoverysedge.mayo.edu/2017/12/01/rocketing-ahead/
is a pioneer in researching senescent cellscells that stop dividing and simply ... leads the discovery research work into cell aging for Mayo Clinic’s Center for Biomedical ... the world’s leading authority on senescent cells as a mentor has defined him as ... Deursen, who earned a doctorate in cell biology in the Netherlands, came to ... their suspected link to aging, senescent cells became his focus. Over