ALS

Gene expression can amplify the risk of neurodegenerative diseases for patients, but researchers are still figuring out which genes have an outsized effect on risk [...]

In preclinical studies, Mayo Clinic scientists and collaborators have identified the molecular mechanism used by the brain's "cleaners" as they remove a problematic protein in [...]

Neuroscientist Tania Gendron, Ph.D. was in her lab on Mayo Clinic’s Florida campus when she received a phone call. On the line was a neurologist [...]

Researchers studying amyotrophic lateral sclerosis, or ALS, have long been suspicious about the protein known as TDP-43. Now, in a new publication in Nature Neuroscience, [...]

Just over five years ago, the lab of neurogeneticist Rosa Rademakers, Ph.D., on Mayo Clinic’s campus in Florida, discovered a genetic mutation that turned the [...]

In the world of scientific research, a decade can go by without major findings on what’s known about a disease. But over the past 10 [...]