ALS

Gene expression can amplify the risk of neurodegenerative diseases for patients, but researchers are still figuring out which genes have an outsized effect on risk ...

In preclinical studies, Mayo Clinic scientists and collaborators have identified the molecular mechanism used by the brain's "cleaners" as they remove a problematic protein in ...

Neuroscientist Tania Gendron, Ph.D. was in her lab on Mayo Clinic’s Florida campus when she received a phone call. On the line was a neurologist ...

Researchers studying amyotrophic lateral sclerosis, or ALS, have long been suspicious about the protein known as TDP-43. Now, in a new publication in Nature Neuroscience, ...

Just over five years ago, the lab of neurogeneticist Rosa Rademakers, Ph.D., on Mayo Clinic’s campus in Florida, discovered a genetic mutation that turned the ...

In the world of scientific research, a decade can go by without major findings on what’s known about a disease. But over the past 10 ...